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Download Citation | High Potency Compounds Manufacturing GMP and Environment Health Safety (EHS) Aspects | The manufacture of highly potent compounds has. With more than 20 years of experience in high potency drug handling and and is manufacturing more than 50 HPAPI compounds for commercialized drug. Partner with us — we provide the most advanced technology for the production and safe containment of your highly potent compound. Our teams are experts in the.

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The concentration of a drug needed to produce 50% maximal response in a given biological system, EC50, is used for comparing the potency of different drugs. Understanding the levels of containment is important when determining the appropriate handling of highly potent compounds. Figure 4 overleaf illustrates the. During review from the board certified toxicologist and development team, Compound X was revealed to be an “ultra-potent” compound, with an OEL in the low.

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Our 20 years of potent drug experience includes multi-step synthesis of a wide range of organic compounds. We currently maintain 15 active Drug Master Files and. Access capabilities for the safe handling, containment and production of highly potent active pharmaceutical ingredients (HPAPI) and cytotoxic compounds. The concentration of a drug needed to produce 50% maximal response in a given biological system, EC50, is used for comparing the potency of different drugs.